2025

• Multiciliated cells adapt the mechanochemical Piezo1-Erk1/2-Yap1 cell proliferation axis to fine-tune centriole number.

  Narayanan V., Rao G. V., Arrigo A., Kulkarni S.S. bioRxiv PMID: 39896494. In review at Science Advances.

• Mechanisms of cilia regeneration in Xenopus multiciliated epithelium in vivo.

Rao, V., Subramanianbalachandar, V. Magaj, M.M., Redemann, S., Kulkarni, S.S. EMBO Reports

2024

• The heterotaxy gene, CCDC11, is important for cytokinesis and cell-cell adhesion via RhoA regulation.

  Kulkarni S.S., Stephenson, R., Amalraj, S., Arrigo, A., Betleja, E., Moresco, J.J., Yates, J.R., Mahjoub, R.M., Miller, A., and Khokha M.K. Cytoskeleton.

2023

• 19th International Xenopus conference meeting report: Latest developments and future perspectives.

Zhou C., and Kulkarni S.S. Developmental Dynamics.

2021

• Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells.

  Kulkarni, S.S., Marquez, J., Date, P., Ventrella, R., Mitchell, B., and Khokha, M. K. eLife.

• Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes.

  Rao, V., and Kulkarni, S.S. Genesis.

  2020

• Corticosterone is essential for survival through frog metamorphosis.

  Shewade, L.H., Schoephoerster, J.A., Patmann, M.D., Kulkarni, S.S., and Buchholz, D.R. Endocrinology.

  2018

• WDR5 stabilizes actin architecture to promote multiciliated cell formation.

  Kulkarni, S.S., Griffin, J.N., Date P.P., Liem, K.F., and Khokha, M.K. Developmental Cell # F1000 Recommended

• WDR5 regulates left-right patterning via chromatin-dependent and independent functions.

  Kulkarni, S.S., and Khokha, M.K. Development. # Selected for Research Highlight

• RPSA, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in Xenopus.

  Griffin, J.N., Sondalle, B.S., Robson, A., Mis, K.E., Griffin, G., Kulkarni, S.S., Deniz, E., Baserga, S., and Khokha, M.K. Development

  2017

• RAPGEF5 regulates the nuclear translocation of β-catenin.

  Griffin, J.N., Del Viso, F., Duncan, A., Robson, A., Kulkarni, S.S., Liu, K., and Khokha, M.K. Developmental Cell.

• Genetic accommodation via modified endocrine signaling explains phenotypic divergence among spadefoot toad species.

  Kulkarni, S.S., Denver, R.J., Gomez-Mestre, I., and Buchholz, D.R. Nature Communications. # Media coverage: Phys.org, Longroom.com, Technology.org, University of Michigan news, Eurekalert.org/ AAAS

  2015

• Comparing techniques for measuring corticosterone in tadpoles.

  Burraco, P., Arribas, R., Kulkarni, S. S., Buchholz, D.R. and Gomez-Mestre, I. Current Zoology.

  2014

• Corticoid signaling in frog metamorphosis.

  Kulkarni, S.S., Buchholz, D.R. General and Comparative Endocrinology.

  2013

• Developmental programs and endocrine disruption of frog metamorphosis: The perspective from microarray analysis.

  Kulkarni, S.S., and Buchholz, D.R. Current Topics in Developmental Biology.

• Mechanisms and Consequences of Developmental Acceleration in Tadpoles Responding to Pond Drying.

  Gomez-Mestre, I., Kulkarni, S. S. and Buchholz, D.R. PLoS One.

  2012

• Beyond synergy: corticosterone and thyroid hormone have numerous interaction effects on gene regulation in Xenopus tropicalis tadpoles.

  Kulkarni, S.S., and Buchholz, D.R. Endocrinology.

  2011

• Evolutionary reduction of developmental plasticity in desert spadefoot toads.

  Kulkarni, S.S., Moskalik, C., Gomez-Mestre, I., Storz, B. and Buchholz, D.R. Journal of Evolutionary Biology.

  2010

• Corticotropin-releasing factor regulates the development in the direct-developing frog, Eleutherodactylus coqui.

  Kulkarni, S.S., Singamsetty, S. and Buchholz, D.R. General and Comparative Endocrinology.

• Hormone regulation and the evolution of frog metamorphic diversity.

  Buchholz, D.R., Moskalik, C., Kulkarni, S.S., Hollar, A. and Ng, A.  Mechanisms of Life History Evolution, Oxford University Press Oxford, 87-97.